Impavido is the first and only FDA-approved drug to treat cutaneous or mucosal leishmaniasis, in addition to Viceral leishmaniasis.

 

Impavido (Miltefosine) is promising with an orphan designation for the treatment of free-living ameba (FLA) infections caused by Naegleria fowleri, Balamuthia mandrillaris, Amebiasis, Schistosomiasis, Granulomatous Amebic
Encephalitis (GAE) and Acanthamoeba species. Use of Impavido with these Orphan Designations is considered "off-label" use at this time.

 

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